Glaukos
This listing was posted on Broadbean.
Bioanalytical Scientist I
Location:
Aliso Viejo, CA
Description:
JOB DESCRIPTION How will you make an impact? Glaukos is a medical technology and pharmaceutical company that's advancing the treatment of ophthalmic diseases. At Glaukos, we are pioneering new treatments for chronic eye diseases and are focused on novel therapies for the treatment of glaucoma (market-leader iStent inject® W), corneal disorders and retinal diseases. Glaukos is looking for a motivated bioanalytical scientist to join the Pharmacokinetics, Drug Disposition, and Clinical Pharmacology team. This team develops and executes the nonclinical and clinical ADME strategy for our novel pharmaceutical products. The team is also responsible for developing and performing liquid chromatography-tandem mass spectrometry (LC-MS/MS) assays to assess local biodistribution, systemic exposure, and quantitation of small molecules and metabolites in biological fluids and tissues.A successful candidate will contribute to internal method development and quantitation efforts and will manage external activities at CROs to provide timely bioanalytical support for Research and Development project teams. This candidate will demonstrate excellent collaboration and communication skills while serving as a subject matter expert advising colleagues from the Applied Research and Translational Sciences group (and other relevant departments) how LC-MS/MS techniques may address key project questions. The ideal candidate would be versatile, self-motivated, timeline and process oriented and demonstrate independent method development skills and the ability to troubleshoot.What will you do? * Perform hands on LC-MS/MS method development, method optimization, fit-for-purpose qualification and non-regulated (non-GLP) bioanalytical sample analysis in a variety of biological fluids and tissues in a timely manner * Coordinate with and monitor external CROs on method development, qualification, validation and sample analysis to enable PK/PD, GLP Tox, and clinical PK studies * Write formal study reports and bioanalytical sections of regulatory documents for submission to regulatory agencies. * Maintain awareness and identify state-of-the-art technologies and methodologies that enhance the department's ability to answer key research and development questions * Maintain state-of-the-art lab equipment (e.g. LC-MS/MS instruments) * Closely collaborate with colleagues in the non-clinical development organization and other relevant departments How will you get here? * Bachelor's degree in chemistry or a closely related discipline, and a minimum of 5-8 years related experience, or Master's degree and 2-5 years of experience, or PhD and 0-4 years of experience * Hands-on experience with development and non-regulated (non-GLP) qualification of LC-MS bioanalytical methods for small molecule drugs and peptides using various techniques (LLE, SPE and immunoprecipitation) in biological fluids and tissues * Familiarity with GLP regulations and bioanalysis-associated FDA and ICH guidances * Experience in collaborating with and monitoring CRO method development, validation, and sample analysis (both non-GLP and GLP) activities to ensure timely delivery of data to project teams * Strong verbal and written communication skills. * Strong organizational skills and keen attention to detail; ability to handle multiple projects in a fast-paced environment * Proven ability to work independently and to collaborate cross-functionally to accomplish goals in a timely manner Preferred Experience: * Familiarity with Sciex LC-MS/MS systems and software. * Additional knowledge of ligand binding assays (e.g. ELISA) is helpful * Basic understanding of pharmacokinetics and drug metabolism is helpful. Generous. Innovative. Leadership-driven. Family-oriented. Socially responsible. These are just a few of the terms our employees use to describe their experiences as a part of the Glaukos family.Those may seem like big aspirations, but here at Glaukos, we recognize the deep significance and profound meaning that comes from knowing that we can make a meaningful difference by helping improve eyesight of people worldwide. And because we're a rapidly growing company with a dynamic, fast-paced culture, individual employees are empowered with more diverse and enriching challenges that might not be possible at a larger company, and more fulfillment in knowing every person and every task is directly tied to making a difference in the life of others.We offer competitive salary (based on experience), bonus eligibility, medical/dental/vision, life insurance, stock options, 401(k) Employer Match, Employee Stock Purchase Program, generous time off & paid holidays as well as time-off to volunteer in the community, plus the opportunity to work for a company that is pioneering a new glaucoma treatment class! Moreover, Glaukos Corporation has been Certified as a Great Place to Work the last three years!Glaukos Corporation is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.ABOUT US Generous. Innovative. Leadership-driven. Family-oriented. Socially responsible. Founded in 1998, Glaukos Corporation is an ophthalmic pharmaceutical and medical technology company focused on developing and commercializing novel therapies for the treatment of glaucoma, corneal disorders, and retinal diseases.Our mission at Glaukos is to truly transform vision by pioneering novel, dropless therapies that can meaningfully advance the standard of care and improve the lives of patients suffering from chronic, sight-threatening eye diseases. Innovation is at the core of everything we do, and we are resolute in our commitment to challenge conventional thinking with new treatment alternatives that are supported by real science, robust clinical evidence, and an unrelenting focus on patients. Our constant pursuit of game-changing technologies that disrupt legacy treatment paradigms is encapsulated in the Glaukos mantra "We'll Go First," which articulates our willingness to take chances, our determination to forge new ground, and our commitment to continuous improvement in all that we do. Our company completed an initial public offering in June of 2015, and our shares are traded on the New York Stock Exchange under the ticker symbol "GKOS". Our global headquarters is in Aliso Viejo, California with additional locations in San Clemente, California, and Burlington, Massachusetts.Glaukos Corporation is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.
Company:
Glaukos
Posted:
April 18 on Broadbean
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More About this Listing: Bioanalytical Scientist I
Bioanalytical Scientist I is a Science & Pharmaceutical Scientist Job at Glaukos located in Aliso Viejo CA. Find other listings like Bioanalytical Scientist I by searching Oodle for Science & Pharmaceutical Scientist Jobs.
Bioanalytical Scientist I is a Science & Pharmaceutical Scientist Job at Glaukos located in Aliso Viejo CA. Find other listings like Bioanalytical Scientist I by searching Oodle for Science & Pharmaceutical Scientist Jobs.