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Postdoctoral Research Scientist or Research Assistant (Immunology) | Research Assistant, Research 1

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Postdoctoral Research Scientist or Research Assistant (Immunology)

Location:
Coatham Mundeville
Description:

We are seeking a Postdoctoral Research Scientist or Research Assistant with a background in immunology and/or molecular biology to lead an exciting new collaboration between the labs of Arianne Richard (Immunology Programme) and Peter Rugg-Gunn (Epigenetics Programme) at the Babraham Institute. Combining the expertise of these two groups, the recruited scientist will investigate the role of epigenetic memory in guiding functional divergence of particular T cell subsets dependent on stimulation history. This project will specifically test whether differentiation and functional responses of effector T cells are impacted by epigenetic memory in their precursor states. To this end, the appointed scientist will i) Compare the epigenetic and functional properties of effector T cells and precursors with different stimulation histories; ii) Test and refine an in vitro system to interrogate causal relationships between epigenetic modifications and T cell effector function. The exciting implication of this work will be to generate new insight into how prior experiences within a T cell lineage shape effector responses and whether this behaviour is encoded by epigenetic memory. This is important because T cell-intrinsic effects of prior exposures have the potential to contribute to differences in immune responses that accumulate over the lifecourse. In addition, characterising the epigenetic effects of stimulation history can ultimately influence the rational design of T-cell-targeting vaccination. The successful candidate will lead this project, designing, carrying out and analysing experiments with input and training from both supervisors and their teams. The post holder will have the opportunity to disseminate their research through conference presentations and publications, train students, expand their skills and network through established collaborations, and benefit from engagement with the Babraham Institute's world-leading scientific community. . Visit ListedBuy for more information.
Company:
Babraham Institute
Posted:
April 12 on ListedBuy
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Postdoctoral Research Scientist or Research Assistant (Immunology) is a Research Research Assistant, Research Scientist Job at Babraham Institute located in United States. Find other listings like Postdoctoral Research Scientist or Research Assistant (Immunology) by searching Oodle for Research Research Assistant, Research Scientist Jobs.